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Mc4r - melanocortin 4 receptor

Alias:
Pkcp
Mc4-r
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个属于黑色素皮质素受体家族的成员。黑色素皮质素受体是跨膜G蛋白耦合受体,响应小肽激素并展示不同的功能和组织类型定位。作为中枢神经系统黑色素皮质素系统的一部分,编码的蛋白质被黑色素细胞刺激激素或agouti相关蛋白竞争性地结合,以调节能量平衡。破坏这个基因促进食欲过盛和肥胖,并与胆固醇水平升高和胰岛素抵抗相关。[由RefSeq,2012年12月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
1
2783 bp
36.96
36
4

Mc4r Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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