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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Mc1r - melanocortin 1 receptor
Alias:
e
Tob
Mcr1
Mshra
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活黑皮质素刺激激素受体的活性。参与细胞内信号传导;正调控细胞内信号传导;以及通过RNA聚合酶II的正调控转录。在黑色素生物合成过程、色素沉着和疼痛感知的感觉传导途径中起上游作用。预测位于膜内。预测是膜的整合成分。预测在细胞质和质膜中活性。在输精管、附睾、食管和皮肤中表达。该基因的人类同源物与家族性黑色素瘤、重度抑郁症、黑色素瘤、II型眼皮肤白化病和色素沉着病有关。与人类MC1R(黑色素皮质素1受体)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:17199
ENSEMBL:ENSMUSG00000074037
UNIPROT:Q01727
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
17199
1
1
3645 bp
35.23
26
3
Mc1r Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Type
Name
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