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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Mbd4 - methyl-CpG binding domain protein 4
Alias:
Med1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有DNA结合活性。在响应DNA损伤、有丝分裂G2 DNA损伤检查点信号传导和辐射反应中,位于内在凋亡信号通路的上游或内部。位于染色质、细胞质和细胞核中。在几个结构中表达,包括中枢神经系统、下泌尿生殖道、生殖系统、视网膜和尿道上皮。该基因的人类同源物与结直肠癌、食管鳞状细胞癌、肺癌和类风湿性关节炎有关。与人类MBD4(甲基-CpG结合结构域4,DNA糖基化酶)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:17193
ENSEMBL:ENSMUSG00000030322
UNIPROT:Q9Z2D7
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
17193
7
8
12704 bp
62.58
6
11
Mbd4 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Abundance
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Cell-specific RNA expression
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Interactions
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Acting
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Score
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Type
Name
MGI
Strain of Origin
Publications
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References Literature
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IF
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