小鼠

Mbd3 - methyl-CpG binding domain protein 3

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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个含有甲基-CpG结合结构域(MBD)的核蛋白家族的成员。编码的蛋白质是组蛋白重塑和组蛋白脱乙酰酶(NuRD)复合物的组成部分。删除这个基因会导致小鼠胚胎致死。缺乏编码的蛋白质的胚胎干细胞在分化能力上受到严重损害,并且在缺乏白血病抑制因子的条件下无法进入发育谱系。可选的剪接导致多个转录变异体,编码不同的异构体。[由RefSeq,2015年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
2
7
6993 bp
32.17
4
7

Mbd3 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
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