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中文人类
DHFR - Dihydrofolate Reductase
Alias:
DYR
DHFR1
DHFRP1
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二氢叶酸还原酶将二氢叶酸转化为四氢叶酸，四氢叶酸是新生合成嘌呤、胸苷酸和某些氨基酸所需的甲基组穿梭工具。虽然功能性的二氢叶酸还原酶基因已被定位到染色体5上，但在其他染色体上已经识别出了多个无内含子的加工假基因或二氢叶酸还原酶样基因。二氢叶酸还原酶缺陷与巨幼细胞性贫血有关。已经发现这个基因有几个编码不同异构体的转录变异体。[由RefSeq，2014年3月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
DHFR Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
