Foxc2 - forkhead box C2

Enables DNA binding activity. Predicted to be involved in several processes, including negative regulation of cold-induced thermogenesis; positive regulation of cell migration involved in sprouting angiogenesis; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including animal organ development; cell surface receptor signaling pathway; and vasculature development. Predicted to be located in nuclear body. Human ortholog(s) of this gene implicated in several diseases, including lymphedema; lymphedema-distichiasis syndrome; obesity; ptosis; and type 2 diabetes mellitus. Orthologous to human FOXC2 (forkhead box C2). [provided by Alliance of Genome Resources, Apr 2022]