Itga2 - integrin subunit alpha 2

Enables collagen binding activity; integrin binding activity; and laminin binding activity. Involved in several processes, including gland development; positive regulation of cell migration; and positive regulation of cellular component organization. Located in several cellular components, including axon terminus; focal adhesion; and perinuclear region of cytoplasm. Biomarker of placental insufficiency. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; artery disease (multiple); blood platelet disease (multiple); diabetes mellitus (multiple); and von Willebrand's disease (multiple). Orthologous to human ITGA2 (integrin subunit alpha 2). [provided by Alliance of Genome Resources, Apr 2022]