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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Pik3ca - phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活1-磷酸肌醇-3-激酶活性。参与几个过程,包括平滑肌细胞增殖的正调控;地塞米松的反应;以及亮氨酸的反应。是磷酸肌醇3-激酶复合物的一部分。常染色体隐性多囊肾病的生物标志物。这个基因的人类同源物涉及几种疾病,包括CLOVES综合征;Cowden综合征5;乳腺癌(多种);皮肤Paget病;和胃肠道系统癌症(多种)。与人类PIK3CA(磷酸肌醇-4,5-二磷酸酯3-激酶催化亚单位α)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:170911
ENSEMBL:ENSRNOG00000056371
UNIPROT:A0A0G2K344
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
170911
2
20
73760 bp
124.35
21
2
Pik3ca Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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