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Pik3ca - phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活1-磷酸肌醇-3-激酶活性。参与几个过程,包括平滑肌细胞增殖的正调控;地塞米松的反应;以及亮氨酸的反应。是磷酸肌醇3-激酶复合物的一部分。常染色体隐性多囊肾病的生物标志物。这个基因的人类同源物涉及几种疾病,包括CLOVES综合征;Cowden综合征5;乳腺癌(多种);皮肤Paget病;和胃肠道系统癌症(多种)。与人类PIK3CA(磷酸肌醇-4,5-二磷酸酯3-激酶催化亚单位α)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
2
20
73760 bp
124.35
21
2

Pik3ca Genetics information (+)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
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