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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Map2k1 - mitogen activated protein kinase kinase 1
Alias:
Mek1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活ATP结合活性;MAP激酶激酶活性;和酶结合活性。参与几个过程,包括囊泡定位的建立;基因表达的调节;和细胞内信号转导的调节。在Ras蛋白信号传导的正调控的上游或内进行。位于几个细胞组件中,包括树突质膜;胞质核周;和细胞质中的核周区域。在谷氨酸能突触和突触后密度中活跃。与微管相关。用于研究白内障和前列腺腺癌。这个基因的人类同源物与癌(多种);3;高等级脑膜瘤;和Melorheostosis有关。与人类MAP2K1(促生长因子激活的蛋白激酶激酶1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:170851
ENSEMBL:ENSRNOG00000010176
UNIPROT:Q01986
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
170851
2
11
71452 bp
43.47
13
17
Map2k1 Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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