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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Crb1 - crumbs family member 1, photoreceptor morphogenesis associated
Alias:
CRB1-A
CRB1-B
CRB1-C
CRB1-A2
7530426H14Rik
A930008G09Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能激活钙离子结合活性。参与视觉感知。在细胞蛋白定位中具有负作用。影响几个过程的上游,包括视觉感知中的光刺激检测、眼睛形态发生和神经发生。位于几个细胞组件中,包括粘附连接、微绒毛和光感受器外段。是细胞顶部的活性部分。在几个结构中表达,包括消化系统、中枢神经系统、表皮、生殖泌尿系统和感光器官。用于研究Leber先天性夜盲8和视网膜色素变性12。该基因的人类同源物与色素性静脉网状脉络膜视网膜退化和视网膜疾病(多种)有关。与人类CRB1(碎屑细胞极性复合物成分1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:170788
ENSEMBL:ENSMUSG00000063681
UNIPROT:Q8VHS2
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
170788
17
12
205975 bp
153.35
20
10
Crb1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
Length(nt)
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* This data comes from NCBI.
Gene Expression
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Name
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