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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Bbc3 - BCL2 binding component 3
Alias:
PUMA
PUMA/JFY1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能够激活ATP酶结合活性。参与几个过程,包括内质网应激反应中的固有凋亡信号通路;对凋亡过程的正向调节;以及对半胱氨酸型内肽酶活性的正向调节。在几个过程的上游或内部发挥作用,包括由p53类介体引起的DNA损伤的响应的内在凋亡信号通路;在凋亡信号通路中参与蛋白质插入线粒体膜的正向调节;以及毒素运输。预测位于线粒体包膜中。预测在线粒体中活性。预测与溶酶体共定位。在几个结构中表达,包括中枢神经系统;免疫系统;肝脏;视网膜;和骨骼肌。该基因的人类同源物与肺非小细胞癌有关。与人类BBC3(BCL2结合成分3)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:170770
ENSEMBL:ENSMUSG00000002083
UNIPROT:Q99ML1
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
170770
10
4
9824 bp
20.75
5
6
Bbc3 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Abundance
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Cell-specific RNA expression
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Interactions
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Score
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Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
References Literature
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PMID
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Year
IF
No Data Found!
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