Slc8b1 - solute carrier family 8 (sodium/lithium/calcium exchanger), member B1

Enables calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential and protein homodimerization activity. Involved in calcium export from the mitochondrion; mitochondrial calcium ion homeostasis; and regulation of lymphocyte chemotaxis. Acts upstream of or within mitochondrial calcium ion transmembrane transport and sodium ion transmembrane transport. Located in mitochondrion and plasma membrane. Is expressed in forelimb bud. Orthologous to human SLC8B1 (solute carrier family 8 member B1). [provided by Alliance of Genome Resources, Apr 2022]