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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Lta4h - leukotriene A4 hydrolase
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质是一种具有水解酶和氨基肽酶活性的酶。水解酶活性用于白细胞三烯B4生物合成的最后步骤,这是一种前炎症介质。氨基肽酶活性已被证明可以降解精氨酸-甘氨酸-精氨酸(PGP),这是一种嗜中性粒细胞的化学吸引剂和慢性阻塞性肺疾病(COPD)的生物标志物。已发现这个基因有两个转录变异体,编码不同的异构体。[RefSeq, 2015年9月提供]
Related ID:
NCBI:16993
ENSEMBL:ENSMUSG00000015889
UNIPROT:P24527
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
16993
2
19
31501 bp
69.05
11
8
Lta4h Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
Gene Expression
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