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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Lrp8 - low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
Alias:
Lr8b
ApoER2
4932703M08Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括:β淀粉样蛋白结合活性;载脂蛋白结合活性;和reelin受体活性。参与多个过程,包括神经系统发育;CREB转录因子活性的正向调节;和树突发育的调节。在中枢神经系统发育和蛋白激酶活性的正向调节中起上游作用或位于中枢神经系统内。位于细胞表面和细胞外空间。在神经系统和视网膜层中表达。此基因的人类同源物与阿尔茨海默病;冠状动脉疾病;痴呆;心肌梗死;和精神分裂症有关。与人类的LRP8(低密度脂蛋白相关蛋白8)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:16975
ENSEMBL:ENSMUSG00000028613
UNIPROT:Q924X6
Basic Information
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Length
MW (kDa)
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16975
46
20
74701 bp
Unknown
11
2
Lrp8 Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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