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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Lrp1 - low density lipoprotein receptor-related protein 1
Alias:
Lrp
A2mr
CD91
b2b1554Clo
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
钙离子结合活性; 货物受体活性; 信号受体结合活性。参与几个过程,包括通过细胞分解过程清除淀粉样-β; 负调控跨膜受体蛋白丝氨酸/苏氨酸激酶信号通路; 和正调控运输。在几个过程的上游或内部发挥作用,包括凋亡细胞的清除; 胆固醇代谢过程; 和心脏发育。位于质膜的外侧。是质膜的整合成分。在几个结构中表达,包括消化系统; 大脑; 胚外成分; 泌尿系统; 和呼吸系统。用于研究阿尔茨海默病; 心肌病; 先天性膈疝; 腹裂; 和肠疝。该基因的人类同源物与阿尔茨海默病; 毛囊性扁平苔藓; 心肌梗死; 和坐骨神经病变有关。与人类LRP1(低密度脂蛋白相关蛋白1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:16971
ENSEMBL:ENSMUSG00000040249
UNIPROT:Q91ZX7
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
16971
2
89
83133 bp
504.74
14
22
Lrp1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
Length(nt)
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CDS(bp)
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* This data comes from NCBI.
Gene Expression
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Name
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