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Lrp1 - low density lipoprotein receptor-related protein 1

Alias:
Lrp
A2mr
CD91
b2b1554Clo
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
钙离子结合活性; 货物受体活性; 信号受体结合活性。参与几个过程,包括通过细胞分解过程清除淀粉样-β; 负调控跨膜受体蛋白丝氨酸/苏氨酸激酶信号通路; 和正调控运输。在几个过程的上游或内部发挥作用,包括凋亡细胞的清除; 胆固醇代谢过程; 和心脏发育。位于质膜的外侧。是质膜的整合成分。在几个结构中表达,包括消化系统; 大脑; 胚外成分; 泌尿系统; 和呼吸系统。用于研究阿尔茨海默病; 心肌病; 先天性膈疝; 腹裂; 和肠疝。该基因的人类同源物与阿尔茨海默病; 毛囊性扁平苔藓; 心肌梗死; 和坐骨神经病变有关。与人类LRP1(低密度脂蛋白相关蛋白1)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
2
89
83133 bp
504.74
14
22

Lrp1 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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