小鼠

Lox - lysyl oxidase

Alias:
rrg
TSC-160
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个属于赖氨酸氧化酶家族的前体蛋白。分泌的前原蛋白在蛋白水解过程中被加工成活性成熟肽和前肽。这个前肽被认为通过抑制Ras信号通路在肿瘤抑制中发挥作用。活性酶在胶原和弹性蛋白的交联中发挥作用,对心血管和呼吸系统发育以及皮肤和结缔组织发育至关重要。可变剪接导致多个转录子变异体。[RefSeq,2013年10月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
3
7
13808 bp
46.70
8
12

Lox Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
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