小鼠

Sh2b3 - SH2B adaptor protein 3

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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码SH2B适配器蛋白家族的一员,该家族在T细胞受体信号传导中扮演重要角色。这个基因在造血干细胞、造血祖细胞、前B细胞和未成熟B细胞以及巨核细胞和肥大细胞中优先表达。在造血干细胞中,编码的蛋白质是自我更新、增殖和凋亡的关键调节因子。缺乏编码的蛋白质的小鼠在脾和骨髓中表现出前B细胞和未成熟B细胞的扩张。可选的剪接导致编码不同异构体的多种转录变异体。[由RefSeq,2015年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
9
9
22163 bp
60.49
4
4

Sh2b3 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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