小鼠

Limk1 - LIM domain kinase 1

Alias:
Limk
KIZ-1
LIMK-1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码LIM激酶家族的蛋白质成员。这种蛋白质是一种通过磷酸化和失活肌动蛋白结合因子cofilin来调节肌动蛋白聚合的丝氨酸/苏氨酸激酶。这种蛋白质还能刺激轴突生长,并在大脑发育中发挥作用。这个基因的纯合性敲除小鼠表现出骨量减少、神经形态异常和突触功能改变。已经发现了这个基因的多个假基因。选择性剪接产生了多种转录变异体。[由RefSeq,2015年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
4
16
33821 bp
72.79
5
17

Limk1 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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