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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Limk1 - LIM domain kinase 1
Alias:
Limk
KIZ-1
LIMK-1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码LIM激酶家族的蛋白质成员。这种蛋白质是一种通过磷酸化和失活肌动蛋白结合因子cofilin来调节肌动蛋白聚合的丝氨酸/苏氨酸激酶。这种蛋白质还能刺激轴突生长,并在大脑发育中发挥作用。这个基因的纯合性敲除小鼠表现出骨量减少、神经形态异常和突触功能改变。已经发现了这个基因的多个假基因。选择性剪接产生了多种转录变异体。[由RefSeq,2015年4月提供]
Related ID:
NCBI:16885
ENSEMBL:ENSMUSG00000029674
UNIPROT:P53668
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
16885
4
16
33821 bp
72.79
5
17
Limk1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
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Cell-specific RNA expression
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Interactions
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Acting
Regulation
Detail
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Score
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Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
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No data available
References Literature
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IF
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