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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Lef1 - lymphoid enhancer binding factor 1
Alias:
Lef-1
3000002B05
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活DNA结合活性;DNA结合转录因子活性,特异性RNA聚合酶II;和染色质结合活性。参与几个过程,包括T辅助1细胞分化;γ-δT细胞分化的正调控;和副腭发育。在几个过程的上游或内部发挥作用,包括动物器官发育;血管形态发生;和RNA聚合酶II的转录调控。位于细胞质和细胞核中。是β-连环蛋白-TCF复合物的一部分。在几个结构中表达,包括消化系统;胚胎外胚层;胚胎中胚层;生殖系统;和皮肤系统。该基因的人类同源物与卵巢癌有关。与人类的LEF1(淋巴增强子结合因子1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:16842
ENSEMBL:ENSMUSG00000027985
UNIPROT:P27782
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
16842
11
12
114035 bp
44.06
9
22
Lef1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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