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Lef1 - lymphoid enhancer binding factor 1

Alias:
Lef-1
3000002B05
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活DNA结合活性;DNA结合转录因子活性,特异性RNA聚合酶II;和染色质结合活性。参与几个过程,包括T辅助1细胞分化;γ-δT细胞分化的正调控;和副腭发育。在几个过程的上游或内部发挥作用,包括动物器官发育;血管形态发生;和RNA聚合酶II的转录调控。位于细胞质和细胞核中。是β-连环蛋白-TCF复合物的一部分。在几个结构中表达,包括消化系统;胚胎外胚层;胚胎中胚层;生殖系统;和皮肤系统。该基因的人类同源物与卵巢癌有关。与人类的LEF1(淋巴增强子结合因子1)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
11
12
114035 bp
44.06
9
22

Lef1 Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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