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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Ldha - lactate dehydrogenase A
Alias:
Ldh1
Ldhm
l7R2
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质在厌氧糖酵解的最终步骤中催化L-乳酸和NAD转化为丙酮酸和NADH。这个蛋白质主要存在于肌肉组织中,属于乳酸脱氢酶家族。这个基因的突变与小鼠的溶血性贫血和早期植入后死亡有关。已经发现这个基因有多个转录变异体,编码不同的异构体。小鼠基因组中包含这个基因的多个假基因。[RefSeq提供,2013年5月]
Related ID:
NCBI:16828
ENSEMBL:ENSMUSG00000063229
UNIPROT:P06151
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
16828
3
8
13354 bp
36.50
17
16
Ldha Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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