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中文小鼠
Lag3 - lymphocyte-activation gene 3
Alias:
Ly66
CD223
LAG-3
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具有MHC II类蛋白结合活性以及跨膜信号受体活性。参与调节性T细胞分化的负调控；浆细胞样树突状细胞的激活；以及免疫应答的调节。位于细胞表面受体信号通路的上游或内部；负调控白细胞介素-2的生成；以及正调控自然杀伤细胞介导的细胞毒性。位于质膜外表面和细胞外区域。与人类LAG3（淋巴细胞激活3）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Lag3 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
