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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Ksr1 - kinase suppressor of ras 1
Alias:
hb
Ksr
RSU2
mKSR1
B-KSR1
D11Bhm183e
D11Bhm184e
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活多种功能,包括14-3-3蛋白结合活性;ATP结合活性;和Hsp90蛋白结合活性。参与细胞内信号传导;调节MAP激酶活性;以及调控细胞群体增殖。在MAPK级联的正向调节的上游或内部发挥作用。预测位于细胞突起和质膜上。预测是含蛋白复合物的一部分。预测在内质网和膜上活性。在多个结构中表达,包括大脑;生殖泌尿系统;肠道;血淋巴样系统腺体;和肺。该基因的人类同源物与乳腺癌有关。与人类KSR1(ras激酶抑制子1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:16706
ENSEMBL:ENSMUSG00000018334
UNIPROT:Q61097
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
16706
12
19
133092 bp
96.75
4
20
Ksr1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Type
Name
MGI
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References Literature
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IF
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