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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Kdr - kinase insert domain protein receptor
Alias:
orv
Flk1
Ly73
Flk-1
Krd-1
VEGFR2
VEGFR-2
sVEGFR-2
6130401C07
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活生长因子结合活性并参与血管内皮生长因子激活的受体活性。参与几个过程,包括循环系统发育;肽基-酪氨酸自磷酸化;以及血管发生的正向调节。在几个过程的上游或内部发挥作用,包括动物器官发育;细胞群增殖的正向调节;和血管系统发育。位于几个细胞组件中,包括细胞连接;内质网;和质膜的外侧。在几个结构中表达,包括消化系统;心血管系统;中枢神经系统;胚外成分;和生殖泌尿系统。该基因的人类同源物涉及几种疾病,包括子宫粘连;动脉疾病(多种);胃肠道系统癌症(多种);黄斑变性(多种);和胰腺癌(多种)。与人KDR(激酶插入域受体)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:16542
ENSEMBL:ENSMUSG00000062960
UNIPROT:P35918
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
16542
6
30
46394 bp
150.46
21
20
Kdr Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
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Type
Name
MGI
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