Kcnma1 - potassium large conductance calcium-activated channel, subfamily M, alpha member 1

Enables identical protein binding activity; large conductance calcium-activated potassium channel activity; and voltage-gated potassium channel activity. Acts upstream of or within several processes, including adult walking behavior; eye blink reflex; and locomotor rhythm. Located in several cellular components, including apical plasma membrane; external side of plasma membrane; and postsynaptic membrane. Is integral component of membrane. Part of voltage-gated potassium channel complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in Alzheimer's disease and idiopathic generalized epilepsy. Orthologous to human KCNMA1 (potassium calcium-activated channel subfamily M alpha 1). [provided by Alliance of Genome Resources, Apr 2022]