Kcnh1 - potassium voltage-gated channel, subfamily H (eag-related), member 1

Enables delayed rectifier potassium channel activity and voltage-gated ion channel activity involved in regulation of presynaptic membrane potential. Involved in potassium ion transmembrane transport; regulation of presynaptic cytosolic calcium ion concentration; and regulation of synaptic vesicle exocytosis. Is integral component of plasma membrane. Is active in parallel fiber to Purkinje cell synapse. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and integumental system. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Orthologous to human KCNH1 (potassium voltage-gated channel subfamily H member 1). [provided by Alliance of Genome Resources, Apr 2022]