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中文人类
AKR1C2 - Aldo-keto Reductase Family 1 Member C2
Alias:
DD
DD2
TDD
BABP
DD-2
DDH2
HBAB
HAKRD
MCDR2
SRXY8
DD/BABP
AKR1C-pseudo
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这个基因编码aldo/keto还原酶超家族的一员，该超家族由40多种已知的酶和蛋白质组成。这些酶使用NADH和/或NADPH作为辅因子，将醛和酮转化为它们相应的醇。这些酶具有重叠但不同的底物特异性。这个酶以高亲和力结合胆汁酸，并显示最小的3-α-羟类固醇脱氢酶活性。这个基因与其他三个基因成员具有高度的序列一致性，并与这些基因在染色体10p15-p14处聚类。已经发现这个基因的三个转录变异体编码两个不同的异构体。[RefSeq，2011年12月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
AKR1C2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
