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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Itgb2 - integrin beta 2
Alias:
2E6
LAD
Cd18
Lfa1
MF17
LCAMB
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
该段英文内容主要描述了ITGB2这个基因的功能、位置、表达和用途。ITGB2是一个位于细胞膜外侧和膜筏上的基因,是整合素αM-β2复合物的一部分,表达在多个系统如消化系统、泌尿系统、心脏和心包、血淋巴系统以及神经系统中。ITGB2参与多种过程,包括低密度脂蛋白颗粒刺激的细胞反应、内吞作用以及白细胞与血管内皮细胞的正调控。此外,ITGB2还位于一些信号通路的上游或内部,包括激活的T细胞增殖、整合素介导的信号通路以及白细胞迁移。该基因用于研究白细胞粘附缺陷1和银屑病。人类ITGB2基因与冠状动脉再狭窄、白细胞粘附缺陷以及白细胞粘附缺陷1有关。
Related ID:
NCBI:16414
ENSEMBL:ENSMUSG00000000290
UNIPROT:P11835
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
16414
4
16
35379 bp
85.03
16
14
Itgb2 Genetics information (+)
GRCm39
Sequence Homology
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Transcript
Length(nt)
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Protein
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* This data comes from NCBI.
Gene Expression
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