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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Itgav - integrin alpha V
Alias:
CD51
1110004F14Rik
2610028E01Rik
D430040G12Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个属于整联蛋白超家族的蛋白质。整联蛋白是参与细胞粘附和信号传导的跨膜受体,根据α和β链的异二聚体形成进行细分。这个蛋白质已被证明可以与β1、β3、β6和β8异二聚化。αv和β3的异二聚体形成了Vitronectin受体。这个蛋白质与几种细胞外基质蛋白相互作用,以调节细胞粘附,并可能在细胞迁移中发挥作用。在鼠中,这个基因的缺陷与脑血管形态发生缺陷和出生后早期死亡有关。[由RefSeq提供,2013年5月]
Related ID:
NCBI:16410
ENSEMBL:ENSMUSG00000027087
UNIPROT:P43406
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
16410
2
30
82466 bp
115.36
8
11
Itgav Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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