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中文小鼠
Itga5 - integrin alpha 5 (fibronectin receptor alpha)
Alias:
Fnra
VLA5
Cd49e
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这个基因的产物属于整合素α链家族。整合素是异源二聚体整膜蛋白，由一个α链和一个β链组成。这个基因编码整合素α5链，通过蛋白水解加工生成轻链和重链，与β1链结合形成纤连蛋白受体。除了粘附作用外，整合素还参与细胞表面信号传导。整合素α5链和整合素αV链由不同的基因产生。这个基因的纯合子敲除小鼠表现出胚胎致死性。可变剪接导致多个转录变异体。[由RefSeq，2015年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Itga5 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
