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Itga2b - integrin alpha 2b

Alias:
CD41
CD41B
GpIIb
alphaIIb
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
能够激活细胞外基质结合活性。在细胞-基质粘附的上游发挥作用。位于质膜外侧和焦点粘附处。在几个结构中表达,包括早期概念囊;泌尿生殖系统;肠道;造血系统;和肝脏。用于研究血小板型出血障碍16。这个基因的人类同源物与Glanzmann's thrombasthenia;血小板型出血障碍16;血小板减少症;和von Willebrand's疾病1有关。与人类ITGA2B(整合素亚单位α2b)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
30
16587 bp
112.68
7
8

Itga2b Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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