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中文人类
CITED4 - Cbp/p300 Interacting Transactivator With Glu/Asp Rich Carboxy-terminal Domain 4
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这个内含子缺失基因编码的蛋白质属于CITED家族的转录共激活因子，通过一个保守的32个氨基酸C端模体与包括CREB结合蛋白(CBP)和p300在内的多种蛋白质结合，调节基因转录。这种蛋白质还与转录因子AP2(TFAP2)相互作用，因此可能作为TFAP2的共激活因子发挥作用。在1p和19q染色体臂缺失的少突胶质瘤中观察到这种基因的高甲基化和转录下调，并且与少突胶质瘤患者的复发无病生存期和总生存期延长有关。[由RefSeq提供，2011年8月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CITED4 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
