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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Insr - insulin receptor
Alias:
IR
IR-A
IR-B
CD220
4932439J01Rik
D630014A15Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个受体酪氨酸激酶家族的成员,这个家族是跨膜信号蛋白,在细胞分化、生长和代谢中扮演重要角色。编码的前原原蛋白经过蛋白水解处理,生成α和β链,形成二硫键连接的异源二聚体,然后进一步异二聚化形成成熟的功能性受体。缺乏编码蛋白的小鼠会出现严重的高血糖和高酮血症,出生后几天内因糖尿病酮症酸中毒死亡。[RefSeq,2016年8月提供]
Related ID:
NCBI:16337
ENSEMBL:ENSMUSG00000005534
UNIPROT:P15208
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
16337
4
21
128728 bp
155.61
13
22
Insr Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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Name
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