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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Inpp5b - inositol polyphosphate-5-phosphatase B
Alias:
5PTase
INPP5P
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个肌醇多磷酸-5-磷酸酶(INPP5)家族的成员。这个蛋白质水解磷脂酰肌醇4,5-二磷酸和磷脂酰肌醇-1,4,5-三磷酸的5'磷酸根,这导致多个信号通路的变化。这个蛋白质可能涉及蛋白质的运输和分泌。同型纯合子敲除小鼠表现出精子发生受损和男性不育。这个基因的可变剪接导致多个转录变异体。[由RefSeq, 2014年11月提供]
Related ID:
NCBI:16330
ENSEMBL:ENSMUSG00000028894
UNIPROT:Q8K337
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
16330
3
24
59685 bp
112.76
5
9
Inpp5b Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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