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中文人类
DCC - DCC Netrin 1 Receptor
Alias:
CRC18
CRCR1
MRMV1
HGPPS2
IGDCC1
NTN1R1
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这个基因编码一个净脉素1受体。这个跨膜蛋白是免疫球蛋白超家族细胞粘附分子的一员，并调节神经元的生长锥朝向净脉素1配体源的轴突引导。胞质尾与酪氨酸激酶Src和粘着斑激酶(FAK,也称为PTK2)相互作用，以调节轴突的吸引力。该蛋白部分定位到脂质筏中，并在无配体的情况下诱导凋亡。该蛋白作为肿瘤抑制因子发挥作用，并在结直肠癌和食管癌中频繁发生突变或下调。[由RefSeq,2009年10月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
DCC Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
