小鼠

Il2 - interleukin 2

Alias:
Il-2
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
能够激活细胞因子活性并参与白细胞介素-2受体的结合活性。在T辅助17细胞分化的负调控中发挥作用。在几个过程的上游或内部发挥作用,包括在无配体情况下的外在凋亡信号通路;大分子代谢过程的正向调控;以及淋巴细胞激活的调控。位于细胞外空间。在肝脏;网膜囊;胸腺;和胸腺原基中表达。用于研究Sjogren's综合征和炎症性肠病。这个基因的人类同源物与几种疾病有关,包括Takayasu's动脉炎;听觉系统疾病(多种);自身免疫疾病(多种);癌(多种);和神经退行性疾病(多种)。与人类IL2(白细胞介素2)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
4
5242 bp
19.40
12
14

Il2 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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