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Il17a - interleukin 17A

Alias:
Il17
Ctla8
IL-17
Ctla-8
IL-17A
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这种基因编码一种促炎性细胞因子,属于白细胞介素-17家族成员。编码的蛋白质在宿主抵抗多种病原体中发挥核心作用。该蛋白质由激活的T细胞和先天免疫系统的某些细胞类型产生。活性蛋白质可以作为同二聚体与其他白细胞介素-17家族成员结合,并通过白细胞介素-17受体传递信号,诱导炎性细胞因子的产生。这种基因的异常表达与自身炎症性疾病有关,包括类风湿性关节炎、银屑病和多发性硬化症。[由RefSeq,2015年9月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
3
3592 bp
17.49
16
25

Il17a Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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