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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Il10 - interleukin 10
Alias:
CSIF
If2a
Il-10
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Description
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一种抗炎细胞因子,属于2类细胞因子家族。编码的蛋白质由先天和适应性免疫系统的细胞分泌,对于限制对广泛病原体的免疫反应至关重要。它还显示能抑制自身免疫反应。这种蛋白质通过特定的白细胞介素10受体复合物传递其免疫抑制信号。这个基因的异常功能与许多免疫紊乱有关,包括移植物抗宿主病,以及HIV-1感染和类风湿关节炎的易感性增加。[RefSeq,2015年9月提供]
Related ID:
NCBI:16153
ENSEMBL:ENSMUSG00000016529
UNIPROT:P18893
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
16153
2
5
5249 bp
20.64
18
12
Il10 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Type
Name
MGI
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References Literature
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IF
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