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中文小鼠
Ikbkg - inhibitor of kappaB kinase gamma
Alias:
NEMO
IKK[g]
1110037D23Rik
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激活依赖K63链接的多泛素修饰的蛋白质结合活性，以及相同的蛋白质结合活性。参与几个过程，包括anoikis；负调控内质网应激诱导的内在凋亡信号通路；以及正调控巨自噬。在B细胞稳态和NF-kappaB诱导的激酶活性的激活中起到上游作用或内部作用。位于细胞质中。在早期概念期、生殖系统和肌肉中表达。用于研究Bloch-Sulzberger综合征和脂肪性肝病。该基因的人类同源物与Behcet病、Bloch-Sulzberger综合征、免疫缺陷33和学习障碍有关。与人类IKBKG（核因子kappa B激酶调节亚基γ的抑制剂）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Ikbkg Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
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Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
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PMID
Journal
Year
IF
