人类

AARS1 - Alanyl-tRNA Synthetase 1

Alias:
AARS
TTD8
CMT2N
DEE29
HDLS2
EIEE29
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
人类丙氨酸-tRNA合成酶(AARS)属于tRNA合成酶家族,属于II类酶。II类tRNA合成酶在进化过程中早期演化且高度保守。这体现在968个残基的polypeptide人类AARS与大肠杆菌蛋白质有41%的相似性。tRNA合成酶是解释RNA密码并将特定氨基酸连接到含有相应三核苷酸反密码子的tRNA上的酶。它们由与tRNA的氨基酸受体-T psi C螺旋相互作用的催化域组成,以及一个与tRNA结构的其他部分相互作用的第二域。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2
21
37209 bp
106.81
1128
8
6
28

AARS1 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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