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中文人类
CYP19A1 - Cytochrome P450 Family 19 Subfamily A Member 1
Alias:
ARO
ARO1
CPV1
CYAR
CYP19
CYPXIX
P-450AROM
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这个基因编码细胞色素P450超家族酶的一员。细胞色素P450蛋白是单加氧酶，催化许多与药物代谢和胆固醇、类固醇和其他脂质合成有关的反应。这种蛋白质定位在内质网，并催化雌激素生物合成的最后步骤。这个基因的突变可能导致芳香酶活性增加或减少；相关的表型提示雌激素既作为性类固醇激素又在生长或分化中发挥作用。可选的启动子使用和可选的剪接导致具有不同组织特异性的多种转录变异体。[RefSeq,2016年12月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CYP19A1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
