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中文人类
CYP8B1 - Cytochrome P450 Family 8 Subfamily B Member 1
Alias:
CP8B
CYP12
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这个基因编码细胞色素P450超家族酶的一员。细胞色素P450蛋白是单加氧酶，催化许多与药物代谢和胆固醇、类固醇和其他脂质的合成有关的反应。内质网膜蛋白催化7α-羟基-4-胆甾-3-酮转化为7α,12α-二羟基-4-胆甾-3-酮。这两种类固醇之间的平衡决定了胆酸和鹅脱氧胆酸相对量的关系，它们都在胆汁中分泌并影响胆固醇的溶解性。这个基因在细胞色素P450基因中是独特的，因为它没有内含子。[RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CYP8B1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
