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中文人类
CYP7A1 - Cytochrome P450 Family 7 Subfamily A Member 1
Alias:
CP7A
CYP7
CYPVII
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这个基因编码细胞色素P450超家族酶的一员。细胞色素P450蛋白是单加氧酶，催化许多与药物代谢和胆固醇、类固醇和其他脂质合成有关的反应。这种内质网膜蛋白催化肝脏胆固醇分解途径中的第一个反应，将胆固醇转化为胆汁酸。这个反应是限速步骤，也是胆汁酸合成的主要调节部位，这是从身体中去除胆固醇的主要机制。这个基因启动子中的多态性与胆汁酸合成缺陷有关。[RefSeq，2010年2月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CYP7A1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
