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中文人类
CYP3A5 - Cytochrome P450 Family 3 Subfamily A Member 5
Alias:
CP35
PCN3
CYPIIIA5
P450PCN3
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这个基因编码细胞色素P450超家族酶的一员。细胞色素P450蛋白是单加氧酶，催化许多与药物代谢和胆固醇、类固醇和其他脂质合成有关的反应。编码的蛋白质代谢药物以及类固醇激素睾酮和孕激素。这个基因是染色体7q21.1上细胞色素P450基因簇的一部分。在这个染色体上的这个簇中已经发现了这个基因的两个假基因。这个基因在种群中的表达广泛变化，影响转录剪接的单核苷酸多态性已被与高血压易感性相关联。选择性剪接导致多个转录变异体。[RefSeq，2014年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CYP3A5 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
