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中文人类
CYP2E1 - Cytochrome P450 Family 2 Subfamily E Member 1
Alias:
CPE1
CYP2E
P450-J
P450C2E
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这个基因编码细胞色素P450超家族酶的一员。细胞色素P450蛋白是单加氧酶，催化许多与药物代谢和胆固醇、类固醇和其他脂质的合成有关的反应。这种蛋白质定位在内质网中，并由乙醇、糖尿病状态和饥饿诱导。这种酶代谢内源底物（如乙醇、丙酮和乙醛）以及外源底物（包括苯、四氯化碳、乙二醇和硝基胺），硝基胺是香烟烟雾中的预突变剂。由于其许多底物，这种酶可能涉及各种过程，如葡萄糖生成、肝硬变、糖尿病和癌症。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CYP2E1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
