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中文人类
GRK2 - G Protein-coupled Receptor Kinase 2
Alias:
BARK1
ADRBK1
BETA-ARK1
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这个基因编码G蛋白偶联受体激酶家族的一员。编码的蛋白质可磷酸化β-肾上腺素受体以及其他广泛的底物，包括非GPCR细胞表面受体、细胞骨架、线粒体和转录因子蛋白质。来自啮齿动物模型的数据支持这个基因在胚胎发育、心脏功能和代谢中发挥作用。这个基因在人类患者中的表达升高与心力衰竭和阿尔茨海默病有关。[RefSeq, 2017年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
GRK2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
