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中文人类
CYP2C9 - Cytochrome P450 Family 2 Subfamily C Member 9
Alias:
CPC9
CYP2C
CYP2C10
CYPIIC9
P450-2C9
P450IIC9
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这个基因编码细胞色素P450超家族酶的一员。细胞色素P450蛋白是单加氧酶，催化许多与药物代谢和胆固醇、类固醇和其他脂质合成有关的反应。这种蛋白质定位在内质网中，其表达受到利福平的诱导。已知这种酶代谢许多外来物质，包括苯妥英、甲苯磺丁脲、布洛芬和S-华法林。研究识别出苯妥英和甲苯磺丁脲的代谢不良的个体，表明这个基因是多态的。这个基因位于染色体10q24上的一个细胞色素P450基因簇内。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CYP2C9 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
