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中文人类
CYP2C19 - Cytochrome P450 Family 2 Subfamily C Member 19
Alias:
CPCJ
CYP2C
P450C2C
CYPIIC17
CYPIIC19
P450IIC19
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这个基因编码细胞色素P450超家族酶的一员。细胞色素P450蛋白是单加氧酶，催化许多与药物代谢和胆固醇、类固醇和其他脂质合成有关的反应。这种蛋白质定位在内质网中，已知其代谢许多外来物质，包括抗惊厥药物美芬妥英、奥美拉唑、地西泮和一些巴比妥类药物。该基因内的多态性与代谢美芬妥英的能力变化相关，称为代谢不良表型和高代谢表型。该基因位于染色体10q24上的细胞色素P450基因簇内。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CYP2C19 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
