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中文小鼠
Htr2c - 5-hydroxytryptamine (serotonin) receptor 2C
Alias:
SR1
5HT1c
Htr1c
5-HT1C
5-HT2C
5-HT-1C
5-HT-2C
5-HT2cR
5-HTR2C
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血清素（5-羟色胺，5-HT）是一种神经递质，通过与多种受体亚型结合而产生广泛的生理效应，包括与七个跨膜结构域的G蛋白偶联受体5-HT2家族，它们激活磷脂酶C和D信号通路。该基因编码血清素2C亚型受体，其mRNA受到多种RNA编辑事件的影响，基因组编码的腺苷酸残基被转化为肌苷。RNA编辑预测会改变5-HT2C受体第二个细胞内环内的氨基酸，并产生具有不同与G蛋白相互作用能力和磷脂酶C和D信号级联激活能力的受体异构体，从而调节中枢神经系统的血清素神经传递。在啮齿动物研究中，显示药物治疗和应激情况下RNA编辑模式发生改变。[RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Htr2c Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
