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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
CYP2B6 - Cytochrome P450 Family 2 Subfamily B Member 6
Alias:
CPB6
EFVM
IIB1
P450
CYP2B
CYP2B7
CYP2B7P
CYPIIB6
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因,CYP2B6,编码细胞色素P450超家族酶的一员。细胞色素P450蛋白是单加氧酶,催化许多与药物代谢和胆固醇、类固醇和其他脂质合成有关的反应。这种蛋白质定位在内质网中,其表达受苯巴比妥诱导。这种酶已知代谢一些外来物质,如抗癌药物环磷酰胺和异磷酰胺。已经描述了这种基因的转录变异体;然而,尚未解决这些转录本是否实际上是由这个基因还是由其紧密相关的假基因CYP2B7产生的。这个基因和假基因都位于19号染色体上CYP2A亚家族的一大群细胞色素P450基因中的一个CYP2A假基因的中部。[由RefSeq,2008年7月提供]
Related ID:
NCBI:1555
ENSEMBL:ENSG00000197408
HGNC:2615
UNIPROT:P20813
OMIM:123930
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
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Reference
1555
1
9
27117 bp
56.28
38
1
14
23
CYP2B6 Genetics information (+)
GRCh38
Sequence Homology
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* This data comes from NCBI.
Gene Expression
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