人类

CYP2B6 - Cytochrome P450 Family 2 Subfamily B Member 6

Alias:
CPB6
EFVM
IIB1
P450
CYP2B
CYP2B7
CYP2B7P
CYPIIB6
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因,CYP2B6,编码细胞色素P450超家族酶的一员。细胞色素P450蛋白是单加氧酶,催化许多与药物代谢和胆固醇、类固醇和其他脂质合成有关的反应。这种蛋白质定位在内质网中,其表达受苯巴比妥诱导。这种酶已知代谢一些外来物质,如抗癌药物环磷酰胺和异磷酰胺。已经描述了这种基因的转录变异体;然而,尚未解决这些转录本是否实际上是由这个基因还是由其紧密相关的假基因CYP2B7产生的。这个基因和假基因都位于19号染色体上CYP2A亚家族的一大群细胞色素P450基因中的一个CYP2A假基因的中部。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
9
27117 bp
56.28
38
1
14
23

CYP2B6 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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