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中文人类
AGR3 - Anterior Gradient 3, Protein Disulphide Isomerase Family Member
Alias:
AG3
AG-3
HAG3
hAG-3
BCMP11
PDIA18
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这个基因编码一种二硫化物异构酶(PDI)家族的成员，该家族是内质网(ER)蛋白质，负责催化蛋白质折叠和巯基-二硫化物交换反应。编码的蛋白质具有N端ER信号序列，具有催化活性的硫氧还蛋白结构域，以及C端ER保留序列。这个基因在纤毛气道上皮细胞中表达，在小鼠中，它在多纤毛细胞中的纤毛搏动频率中发挥作用。这个基因在乳腺癌、卵巢癌和前列腺癌中过度表达。[RefSeq提供，2016年12月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
AGR3 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
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Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
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CAS Number
Status
Phase
Link
References Literature
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PMID
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Year
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